Kishore Nagasubramanian is a postdoctoral fellow with a research interest in understanding how immune dysregulation contributes to chronic inflammatory diseases and tissue dysfunction. He completed his Ph.D. in Neuroimmunoinformatics at SASTRA Deemed University, where he investigated the role of immune regulatory mechanisms in neuroinflammation, with a focus on how immune signaling pathways influence neurological disease progression.His current research focuses on understanding how aging influences immune cell function and tissue remodeling during chronic diseases, particularly lung fibrosis and macrophage-driven inflammation. He aims to uncover how age-associated alterations in immune regulation, macrophage states, and lipid metabolism contribute to the transition from tissue repair responses toward persistent inflammation and fibrosis.His broader research interests include immune aging, macrophage biology, lipid-associated macrophages, inflammation-associated tissue remodeling, neuroinflammation, and the molecular mechanisms governing immune-mediated diseases.
Identification of small molecule modulators of class II transactivator-I using computational approaches. Journal of Biomolecular Structure and Dynamics, 2023 (Kishore N, S Jha, AS Rathore, K Gupta)
Implications of Asparagus racemosus and Terminalia chebula extracts on oxazolone induced inflammatory bowel disease in Danio rerio (zebrafish). Biocatalysis and Agricultural Biotechnology, 2023 (Kishore N, S Balakumar, CD Raj, N Sivakumar, R Thirumalaisamy, et al.)
Interactome analysis implicates class II transactivator (CIITA) in depression and other neuroinflammatory disorders. International Journal of Neuroscience, 2024 (Kishore N, K Gupta)
Interactome and Expression Profile of Class II Transactivator (CIITA) in Lipopolysaccharides mediated neuroinflammation: A Combined Network Analysis and Zebrafish Model Study. In Silico Research in Biomedicine, 2025 (Kishore N)
Inhibitor screening identifies Entecavir as a promising candidate targeting human eIF4E to block cap-dependent translation in cancer: an integrated in silico and in vitro study. Journal of Computer-Aided Molecular Design, 2026 (Kishore N, P Vincent, KK Gupta, SA Chandran)